Researcher's space

How to request samples at the Neuro-CEB Biobank?

For a sample request, please contact the engineer of the Neuro-CEB Biological Resource Center, Mme Sabrina Leclère, who will send you a request form, or download the form on this page (see below). Fill in the request form and the MTA. Send one version by e-mail and the original document by regular mail. Your sample request will be examined by the Neuro-CEB Biobank scientific committee. The response time is two weeks as a mean.

When using samples, you must be aware that being from human origin, they should be treated with special care.

The provided samples have been collected post mortem by the Neuro-CEB network. The patients have given their consent during their lifetime in a generous way to help scientific research in neurodegenerative diseases. The Neuro-CEB Biobank wants to guarantee the proper use of the samples. When using the samples, you must accept the following principles:

  • to respect the law concerning the use of human samples in research
  • to use the samples exclusively for the project that has been submitted in the request form
  • to use samples for scientific projects that are not directly commercial
  • to let the Neuro-CEB coordinator know when the project has ended
  • to complete the form sent by the Neuro-CEB brain bank concerning the progress of the project, the published papers and the assessment of the service quality
  • to mention the "Neuro-CEB network" in the authors of the paper when the collaboration has been significant, or in he acknowledgement when the collaboration has been limited.

List of available samples

2019/11/28

DEMENTIAS NUMBER OF CASES
Vascular dementia 6
Alzheimer disease 190
Lobar Fronto-Temporal Dementia 45
Lobar Fronto-Temporal Dementia + Amyotrophic Lateral Sclerosis 11
Amyotrophic Lateral Sclerosis 7
TAUOPATHIES NUMBER OF CASES
Pick disease 4
Corticobasal degeneration 16
Progressive Supranuclear Palsy 42
Lobar Fronto-Temporal Dementia (Tau) 7
Posterior Cortical Atrophy 4
SYNUCLEINOPATHIES NUMBER OF CASES
Lewy bodies dementia +Alzheimer disease 12
Lewy bodies dementia 17
Parkinson disease +Alzheimer disease 123
Parkinson disease 17
NUMBER OF CASES
Cerebellar atrophies 14
Multiple Sclerosis 11
Control 28

Available samples

Sampling protocols depend on the disease. Several methods of conditioning are available:

  • Large samples (frozen on dry ice) used for biochimical, proteomic or genetic studies
  • Small samples mounted on cork, frozen in liquid nitrogen cooled isopentane used for morphologic studies

The samples involve the following regions:

  • multiple cortical areas
  • subcortical nuclei
  • brainstem
  • cerebellum
  • in some cases, the spinal cord

New, prospective protocols may be implemented to meet the scientists' needs.

Please notice that the absence of PrPs (Creutzfeldt-Jacob disease) is checked in all the cases

Questions ?

Feel free to check our  Frequently Asked Questions or to contact the engineer in charge of the biobank: 

Sabrina Leclère

  • Phone : (+33 1).42.17.75.09 (office hours)
  • Email : ingenieur.neuroceb.psl@aphp.fr
  • Address : Biobanque Neuro-CEB - Plateforme de Ressources Biologiques - Hôpital de la Pitié-Salpêtrière - 47 bd de l'hôpital 75651 Paris cedex 13 - France